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Boron influences immune and antioxidant responses by modulating hepatic superoxide dismutase activity under calcium deficit abiotic stress in Wistar rats.

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Title Boron influences immune and antioxidant responses by modulating hepatic superoxide dismutase activity under calcium deficit abiotic stress in Wistar rats.
Not Available
 
Creator Vijay BT
Gowda NKS
Mondal S
Krishnamoorthy P
Pal DT
Mor A
Karthik Bhat S
Pattanaik AK
 
Subject Antioxidant
Boron
Immunity
Superoxide dismutase
 
Description Not Available
The influence of Boron (B) supplementation on immune and antioxidant status of rats with or without abiotic stress induced by dietary calcium (Ca) restriction was studied in a feeding trial of 90 days. Wistar strain rats (3-4 wk age, n=84) were divided into 7 dietary groups (4 replicates of 3 each) viz., normal-calcium (100%) basal diet alone (NC, control) or supplemented with B at 5 (NCB-5), 10 (NCB-10), 20 (NCB-20) and 40ppm (NCB-40) levels; low-calcium (50%) basal diet alone (LC) or supplemented with 40ppm B (LCB-40). After 75 days of experimental feeding, rats were challenged with intraperitoneal injection of sheep RBCs to assess their humoral immunity. At the end of the trial, cell-mediated immunity was assessed as foot pad reaction to sheep RBCs injected into the hind leg paws. Eight rats from each group were sacrificed to collect blood for estimation of minerals and total antioxidant activity, and liver for superoxide dismutase gene expression analysis. Supplementation of graded levels of B (5, 10, 20 and 40ppm) as borax in NC diets significantly increased (P
Not Available
 
Date 2018-11-25T01:47:33Z
2018-11-25T01:47:33Z
2016-01-01
 
Type Research Paper
 
Identifier Vijay BT, Gowda NKS, Mondal S, Krishnamoorthy P, Pal DT, Mor A, Karthik Bhat S and Pattanaik AK. 2016. Boron influences immune and antioxidant responses by modulating hepatic superoxide dismutase activity under calcium deficit abiotic stress in Wistar rats. Journal of Trace Elements in Medicine and Biology, 36:73-79.
0946-672X
http://krishi.icar.gov.in/jspui/handle/123456789/13213
 
Language English
 
Relation Not Available;
 
Publisher Europe PMC