Boron influences immune and antioxidant responses by modulating hepatic superoxide dismutase activity under calcium deficit abiotic stress in Wistar rats.
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Title |
Boron influences immune and antioxidant responses by modulating hepatic superoxide dismutase activity under calcium deficit abiotic stress in Wistar rats.
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Creator |
Vijay BT
Gowda NKS Mondal S Krishnamoorthy P Pal DT Mor A Karthik Bhat S Pattanaik AK |
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Subject |
Antioxidant
Boron Immunity Superoxide dismutase |
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Description |
Not Available
The influence of Boron (B) supplementation on immune and antioxidant status of rats with or without abiotic stress induced by dietary calcium (Ca) restriction was studied in a feeding trial of 90 days. Wistar strain rats (3-4 wk age, n=84) were divided into 7 dietary groups (4 replicates of 3 each) viz., normal-calcium (100%) basal diet alone (NC, control) or supplemented with B at 5 (NCB-5), 10 (NCB-10), 20 (NCB-20) and 40ppm (NCB-40) levels; low-calcium (50%) basal diet alone (LC) or supplemented with 40ppm B (LCB-40). After 75 days of experimental feeding, rats were challenged with intraperitoneal injection of sheep RBCs to assess their humoral immunity. At the end of the trial, cell-mediated immunity was assessed as foot pad reaction to sheep RBCs injected into the hind leg paws. Eight rats from each group were sacrificed to collect blood for estimation of minerals and total antioxidant activity, and liver for superoxide dismutase gene expression analysis. Supplementation of graded levels of B (5, 10, 20 and 40ppm) as borax in NC diets significantly increased (P Not Available |
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Date |
2018-11-25T01:47:33Z
2018-11-25T01:47:33Z 2016-01-01 |
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Type |
Research Paper
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Identifier |
Vijay BT, Gowda NKS, Mondal S, Krishnamoorthy P, Pal DT, Mor A, Karthik Bhat S and Pattanaik AK. 2016. Boron influences immune and antioxidant responses by modulating hepatic superoxide dismutase activity under calcium deficit abiotic stress in Wistar rats. Journal of Trace Elements in Medicine and Biology, 36:73-79.
0946-672X http://krishi.icar.gov.in/jspui/handle/123456789/13213 |
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Language |
English
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Relation |
Not Available;
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Publisher |
Europe PMC
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