One-step Multiplex Transgenesis via Sleeping Beauty Transposition in Cattle
KRISHI: Publication and Data Inventory Repository
View Archive InfoField | Value | |
Title |
One-step Multiplex Transgenesis via Sleeping Beauty Transposition in Cattle
Not Available |
|
Creator |
Wiebke Garrels1,2,*, Thirumala R. Talluri1,*,†, Ronja Apfelbaum1, Yanet P. Carratalá1,3, Pablo Bosch4, Kerstin Pötzsch5, Esther Grueso5, Zoltán Ivics5 & Wilfried A. Kues1
|
|
Subject |
transgenesis, cattle, sleeping beauty, piggybac
|
|
Description |
Not Available
Genetically modified cattle are important for developing new biomedical models and for an improved understanding of the pathophysiology of zoonotic diseases. However, genome editing and genetic engineering based on somatic cell nuclear transfer suffer from a low overall efficiency. Here, we established a highly efficient one-step multiplex gene transfer system into the bovine genome. |
|
Date |
2019-05-23T10:38:23Z
2019-05-23T10:38:23Z 2016-02-24 |
|
Type |
Article
|
|
Identifier |
Not Available
Not Available http://krishi.icar.gov.in/jspui/handle/123456789/19811 |
|
Language |
English
|
|
Relation |
Not Available;
|
|
Publisher |
Nature.com
|
|