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One-step Multiplex Transgenesis via Sleeping Beauty Transposition in Cattle

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Title One-step Multiplex Transgenesis via Sleeping Beauty Transposition in Cattle
Not Available
 
Creator Wiebke Garrels1,2,*, Thirumala R. Talluri1,*,†, Ronja Apfelbaum1, Yanet P. Carratalá1,3, Pablo Bosch4, Kerstin Pötzsch5, Esther Grueso5, Zoltán Ivics5 & Wilfried A. Kues1
 
Subject transgenesis, cattle, sleeping beauty, piggybac
 
Description Not Available
Genetically modified cattle are important for developing new biomedical models and for an improved
understanding of the pathophysiology of zoonotic diseases. However, genome editing and genetic
engineering based on somatic cell nuclear transfer suffer from a low overall efficiency. Here, we
established a highly efficient one-step multiplex gene transfer system into the bovine genome.
 
Date 2019-05-23T10:38:23Z
2019-05-23T10:38:23Z
2016-02-24
 
Type Article
 
Identifier Not Available
Not Available
http://krishi.icar.gov.in/jspui/handle/123456789/19811
 
Language English
 
Relation Not Available;
 
Publisher Nature.com