Expression patterns of candidate genes reflecting the growth performance of goats subjected to heat stress
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Title |
Expression patterns of candidate genes reflecting the growth performance of goats subjected to heat stress
Not Available |
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Creator |
Angel SP
Bagath M Sejian V Krishnan G Bhatta R |
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Subject |
Climate change
Goat Growth hormone Heat stress IGF-1 Leptin |
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Description |
Not Available
The study is an attempt to elucidate the molecular mechanisms governing growth performance during heat stress in goats. The primary objective of the study was to establish the influence of heat stress on the expression patterns of different growth related genes in Malabari goats. The study was conducted for a period of 45 days in 12 Malabari goats randomly allocated into two groups: MC (n = 6; Malabari control) and MHS (n = 6; Malabari heat stress). At the end of study period, all 12 animals were slaughtered and their liver tissues were collected for gene expression and histopathological studies. The temperature-humidity-index (THI) inside the shed (74.9) proved that the animals were not stressed while in the outside environment (86.5) the animals were extremely distressed. The hepatic growth hormone (GH), growth hormone receptor (GHR), insulin-like growth factor-1 (IGF-1), leptin (LEP) and leptin receptor (LEPR) gene expression patterns were significantly (P ICAR-NIANP |
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Date |
2019-11-15T05:56:15Z
2019-11-15T05:56:15Z 2018-10-20 |
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Type |
Research Paper
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Identifier |
Angel SP, Bagath M, Sejian V, Krishnan G, Bhatta R. 2018. Expression patterns of candidate genes reflecting the growth performance of goats subjected to heat stress. Molecular Biology Reports, 45:2847-2856.
0301-4851 (Print) 1573-4978 (Online) http://krishi.icar.gov.in/jspui/handle/123456789/24735 |
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Language |
English
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Relation |
Not Available;
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Publisher |
Spinger
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