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Cloning and sequence analysis of b-tubulin gene of Trypanosoma evansi isolates from Indian dromedaries (Camelus dromedarius).

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Title Cloning and sequence analysis of b-tubulin gene of Trypanosoma evansi isolates from Indian dromedaries (Camelus dromedarius).
Not Available
 
Creator M. Ashraf
Meera Srivastava
S.K. Ghorui
G. Nagarajan
Shelesh kumar Swami
Sanjay Kumar.
 
Subject ß tubulin gene
Dromedarian camel
Phylogenetic analysis
T. evansi
 
Description Not Available
Trypanosomosis caused by Trypanosoma evansi is a disease of economic significance of domestic livestock, causing trypanosomiasis, commonly known as Surra. In the present study, gene of Trypanosoma evansi have beer cloned and sequenced. Beta-tubulin is important for cellular structure and physical functions. Sequence analysis of this gene will be useful for the vaccine studies. The open reading frame of b-tubulin of Trypanosoma evansi is 1329 bp in length, encoding 442 amino acid polypeptide. The sequence analysis revealed that the ß tubulin gene of Trypanosoma evansi from India was having the identity of 99% with T.equiperdum, T.evansi (China isolate), T.evansi (Indian isolates), T.brucei and 88% with T.cruzi. The stable biological characteristics of Trypanosomatidae beta-tubulin make it an ideal target of many anti-parasitic drugs that block tubulin function.
Not Available
 
Date 2020-03-13T06:33:38Z
2020-03-13T06:33:38Z
2015-01-01
 
Type Article
 
Identifier Not Available
0367-6722
http://krishi.icar.gov.in/jspui/handle/123456789/33792
 
Language English
 
Relation Not Available;
 
Publisher Not Available