Cloning and sequence analysis of b-tubulin gene of Trypanosoma evansi isolates from Indian dromedaries (Camelus dromedarius).
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Title |
Cloning and sequence analysis of b-tubulin gene of Trypanosoma evansi isolates from Indian dromedaries (Camelus dromedarius).
Not Available |
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Creator |
M. Ashraf
Meera Srivastava S.K. Ghorui G. Nagarajan Shelesh kumar Swami Sanjay Kumar. |
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Subject |
ß tubulin gene
Dromedarian camel Phylogenetic analysis T. evansi |
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Description |
Not Available
Trypanosomosis caused by Trypanosoma evansi is a disease of economic significance of domestic livestock, causing trypanosomiasis, commonly known as Surra. In the present study, gene of Trypanosoma evansi have beer cloned and sequenced. Beta-tubulin is important for cellular structure and physical functions. Sequence analysis of this gene will be useful for the vaccine studies. The open reading frame of b-tubulin of Trypanosoma evansi is 1329 bp in length, encoding 442 amino acid polypeptide. The sequence analysis revealed that the ß tubulin gene of Trypanosoma evansi from India was having the identity of 99% with T.equiperdum, T.evansi (China isolate), T.evansi (Indian isolates), T.brucei and 88% with T.cruzi. The stable biological characteristics of Trypanosomatidae beta-tubulin make it an ideal target of many anti-parasitic drugs that block tubulin function. Not Available |
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Date |
2020-03-13T06:33:38Z
2020-03-13T06:33:38Z 2015-01-01 |
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Type |
Article
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Identifier |
Not Available
0367-6722 http://krishi.icar.gov.in/jspui/handle/123456789/33792 |
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Language |
English
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Relation |
Not Available;
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Publisher |
Not Available
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