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Computational Modelling of Tetraodon nigroviridis Melanocortin-1 Receptor (MC1R) Protein and Identification of Natural Compounds as Putative Modulators.
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View Archive Info| Field | Value | |
| Title |
Computational Modelling of Tetraodon nigroviridis Melanocortin-1 Receptor (MC1R) Protein and Identification of Natural Compounds as Putative Modulators.
Not Available |
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| Creator |
Pandey Saumya and Shrinivas Jahageerdar*.
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| Subject |
BLAHtetrone, Docking, G-protein coupled receptor, Homology modeling, Virtual screening
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| Description |
Not Available
In ornamental fisheries, body ornamentation, including the body colour, is of great economic importance. Melanocortin-1 receptor (MC1R) gene is primarily responsible for pigmentation in the majority of the vertebrates, and its modulation will help to understand the pigmentation and external body coloration. The present study was aimed to predict the MC1R tertiary protein structure of Tetraodon nigroviridis through homology modelling and to identify putative modulators. The tertiary protein structure of the MC1R protein of T. nigroviridis was homology modelled and validated. BLAHtetrone with binding efficiency of -9.7 kcal/mol was identified as a putative modulator of the MC1R protein Not Available |
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| Date |
2022-06-16T04:45:43Z
2022-06-16T04:45:43Z 2020-05-21 |
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| Type |
Research Paper
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| Identifier |
Not Available
Not Available http://krishi.icar.gov.in/jspui/handle/123456789/72596 |
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| Language |
English
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| Relation |
Not Available;
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| Publisher |
NISCAIR
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