ICAR Research Data Repository for Knowledge Management
Monoclonal antibodies against foot-and-mouth disease virus RNA polymerase for detection of virus infection.
KRISHI: Publication and Data Inventory Repository
View Archive Info| Field | Value | |
| Title |
Monoclonal antibodies against foot-and-mouth disease virus RNA polymerase for detection of virus infection.
Not Available |
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| Creator |
Anand K, Subhasmita B, Mani S, Sreedharan K, Suresh B, Reddy GBM, Madhusudan H
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| Subject |
Monoclonal, antibodies, RNA, virus infection, FMD virus
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| Description |
Not Available
Foot-and-mouth disease (FMD) is a major viral disease in farm animals. In the present study, seven monoclonal antibodies (mAbs) were produced against the FMD virus (FMDV)-encoded RNA-dependent RNA polymerase (3D protein) and characterized. Screening of mAb reactivity against three overlapping fragments of the 3D protein expressed in Escherichia coli revealed that the binding sites of all the mAbs were confined to the N-terminal one-third of the 3D protein. A selected mAb was utilized for detecting FMDV in the infected cell culture and tissues obtained from FMDV-infected animals. Not Available |
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| Date |
2022-06-20T04:46:45Z
2022-06-20T04:46:45Z 2020-11-17 |
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| Type |
Research Paper
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| Identifier |
Not Available
Not Available http://krishi.icar.gov.in/jspui/handle/123456789/73049 |
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| Language |
English
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| Relation |
Not Available;
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| Publisher |
WILEY
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