Microbiome of Pukzing Cave in India shows high antimicrobial activity against plant and animal pathogens
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Title |
Microbiome of Pukzing Cave in India shows high antimicrobial activity against plant and animal pathogens
Not Available |
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Creator |
M.A. Iquebal
Ajit Kumar Passari Jaisri Jagannadham Farzana Ahmad Vincent Vineeth Leo Garima Singh Sarika Jaiswal Anil Rai Dinesh Kumar Bhim Pratap Singh |
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Subject |
Antimicrobial peptides
Biosynthetic genes Cave microbial diversity Moderate thermophiles 16s rDNA |
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Description |
Not Available
Pukzing cave, the largest cave of Mizoram, India was explored for bacterial diversity. Culture dependent method revealed 235 bacterial isolates using three different treatments. Identity of the microbial species was confirmed by 16S rDNA sequencing. The highest bacterial population was recovered from heat treatment (n = 97;41.2%) followed by normal (n = 79;33.6%) and cold treatment (n = 59;25.1%) indicating dominance of moderate thermophiles. Antimicrobial potential of isolates showed 20.4% isolates having antimicrobial ability against tested pathogens. Amplicon sequencing of PKSI, PKSII and NRP specific genes revealed presence of AMP genes in the microbial population. Six microbial pathogens were selected for screening as they are well known for different disease cause organism in various fields such as agriculture and human health. Cave environment harbors unique microbial flora and hypervariable region V4 is more informative. Higher activity of AMP assay against these microbes indicates that cave microbial communities could be potential source of future genomic resources. Not Available |
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Date |
2022-03-15T09:30:53Z
2022-03-15T09:30:53Z 2021-11-01 |
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Type |
Research Paper
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Identifier |
M.A. Iquebal, Ajit Kumar Passari, Jaisri Jagannadham, Farzana Ahmad, Vincent Vineeth Leo, Garima Singh, Sarika Jaiswal, Anil Rai, Dinesh Kumar, Bhim Pratap Singh, Microbiome of Pukzing Cave in India shows high antimicrobial activity against plant and animal pathogens, Genomics, Volume 113, Issue 6, 2021, Pages 4098-4108, ISSN 0888-7543, https://doi.org/10.1016/j.ygeno.2021.10.004.
Not Available http://krishi.icar.gov.in/jspui/handle/123456789/70238 |
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Language |
English
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Relation |
Not Available;
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Publisher |
Elsevier
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