ICAR Research Data Repository for Knowledge Management
In vitro biological activities of new heterocyclic chalconederivatives
KRISHI: Publication and Data Inventory Repository
View Archive Info| Field | Value | |
| Title |
In vitro biological activities of new heterocyclic chalconederivatives
|
|
| Creator |
Darshan Raj CG, Sarojini BK, Hegde S, Sreenivasa , Ravikumar, YS, Bhanuprakash V, Revanaiah Y, Ragavendra R
|
|
| Subject |
Novel heterocyclic chalcone derivatives, Antioxidant activity, Antimicrobial property, Antiviral studies
|
|
| Description |
This work reports the synthesis and character-ization of new heterocyclic chalcone derivatives 3(a–j) andin vitro biological evaluation for antiproliferative, antiox-idant, antibacterial, antifungal, and antiviral properties. The antiproliferative efficacy and LC50 of the compoundsagainst HepG2 cell lines were determined. The LC50 for 3dwas found to be 8 lg/mL. All the compounds exhibitedmoderate DPPH scavenging activity and moderate to goodantimicrobial activity against tested bacterial and fungalstrains. Further, the compounds at their respective maxi-mum non-toxic concentrations did not inhibit DNA viruseslike buffalopox, camelpox, and goatpox.
|
|
| Date |
2023-05-16T09:37:04Z
2023-05-16T09:37:04Z 2012-01-01 |
|
| Type |
Research Paper
|
|
| Identifier |
http://krishi.icar.gov.in/jspui/handle/123456789/77492
|
|
| Language |
English
|
|
| Publisher |
Springer
|
|